Lettuce (Lactuca sativa) withstands light frosts and is one of the easiest cool-season vegetables to grow. High summer temperatures usually cause seed stalk formation (bolting) and bitter flavor. Slow-bolting or heat-resistant varieties are available and are recommended for extending the lettuce-growing season.

Lettuce (Lactuca sativa) is one of the easiest cool season vegetables to grow.

Lettuce (Lactuca sativa) is one of the easiest cool season vegetables to grow.
Barbara H. Smith, ©2017 HGIC, Clemson Extension

Most gardeners who grow lettuce raise the loose-leaf type, with either green or reddish leaves. This type is a fast-growing, long-lasting lettuce used for salads and sandwiches. Leaf lettuce needs only to be planted and harvested.

Butterhead or Bibb lettuce is a loose-heading type with dark green leaves that are somewhat thicker than those of iceberg lettuce. Butterheads develop a light yellow, buttery appearance and are very attractive in salads. A miniature variety of butterhead, Tom Thumb, is very easy to grow and requires a short growing time of 70 days. Bibb lettuce will develop bitterness readily if temperatures go above 75 °F.

Romaine or cos is less commonly grown by gardeners, but is a very nutritious lettuce that deserves consideration. It too is relatively easy to grow, forming upright heads with rather wavy, attractive leaves.

Crisphead, also known as iceberg, has a tightly compacted head with crisp, light green leaves. Many South Carolina gardeners find this type difficult to grow due to its lack of heat tolerance.


Lettuce is a cool-season crop that prefers temperatures of 55 to 65 °F for optimum growth. This crop prefers a loamy soil with a high organic matter content. Lettuce seedlings should be protected from the wind because the young plants are rapidly dried out. Use a handful of pine needles around tender seedlings to help prevent wind damage and also provide support.

The optimum soil temperature for seed germination is 60 to 80 °F. Raw lettuce seed will not germinate at a soil temperature above 95 °F. Use primed seed if possible. Priming is a water-based process performed on seed that increases germination rate, decreases germination time, and will aid in establishing a better crop stand. Primed seed will ensure optimum seed germination at varying temperatures. Buy only certified fungicide-treated seed from a reputable source.

Planting Dates

Area Spring Fall
Piedmont Mar 1 – May 15 Not recommended
Coastal Feb 1 – Apr 15 Sept 5 – Nov 1
South Carolina Gardening Regions

South Carolina Gardening Regions

Piedmont: Abbeville, Anderson, Cherokee, Chester, Chesterfield, Edgefield, Fairfield, Greenville, Greenwood, Kershaw, Lancaster, Laurens, Marlboro, McCormick, Newberry, Oconee, Pickens, Saluda, Spartanburg, Union, and York Counties.

Coastal Plain: Aiken, Allendale, Bamberg, Barnwell, Beaufort, Berkeley, Calhoun, Charleston, Clarendon, Colleton, Darlington, Dillon, Dorchester, Florence, Georgetown, Hampton, Horry, Jasper, Lee, Lexington, Marion, Orangeburg, Richland, Sumter, and Williamsburg Counties.

Plant leaf lettuce in rows 1 to 2 feet apart with seed one-quarter inch deep and 6 to 10 inches apart in the row. It is difficult to space this small seed precisely at the desired spacing; therefore, it will usually be necessary to plant thicker and thin the planting. Leaf lettuce should be thinned when the plants are 1 to 2 inches tall. Leaf lettuce can also be planted in 12-inch-wide beds with the seed broadcast over the bed.

Head lettuce should be planted in rows 3 feet apart with 12 inches between plants in the row. It is best to grow head lettuce from transplants purchased from a reputable garden center.

The soil should be well-prepared to provide good seed-to-soil contact and ensure rapid stand establishment of this small-seeded crop. Soil crusting over the developing seedlings may make it difficult to obtain a good stand, especially on heavy clay soils. Covering the seed with potting soil instead of garden soil will eliminate crusting problems.

Recommended Cultivars

  • Green Leaf – Green Ice, Grand Rapids, Simpson Elite, Slobolt
  • Red Leaf – Lolla Rosa, New Red Fire, Red Head, Red Sails
  • Boston – Buttercrunch, Esmeralda
  • Head – Great Lakes, Ithaca, Nevada, Raider, Summertime
  • Romaine – Darkland, Defender, Green Forrest, Ideal Cos, King Henry, Parris Island Cos, Sunbelt, Tall Guzmaine
Defender lettuce is a romaine type that has dark green leaves.

Defender lettuce is a romaine type that has dark green leaves.
Barbara H. Smith, ©2017 HGIC, Clemson Extension


A soil test is always the best method for determining the fertilization needs of a crop. Follow the results of a soil test to maintain a soil pH between 6.0 and 6.5 and optimal fertility levels. If required, lime the soil at least 3 months in advance. Information on soil testing is available in HGIC 1652, Soil Testing.

If a soil test has not been taken, apply 5-10-10 at 3 pounds per 100 square feet before planting. Lettuce should be sidedressed once during the growing season. Sidedress with calcium nitrate (15-0-0) at 2 pounds per 100 feet of row. More frequent sidedressing may be required if the garden is sandy or if excessive rains occur. Nitrogen is important for these crops to produce a high-quality, dark green product.


Water the garden frequently to maintain a uniform moisture supply during growth. The garden should be watered in the morning so that the foliage is dry before dark. Water the garden sufficiently to moisten the soil to a depth of 6 inches. Light sprinklings will encourage shallow rooting of the plants. The most critical period for moisture is during stand establishment. It is important to have a constant uniform moisture supply to produce a high-quality crop.

Cultural Practices

To have a continuous supply of leaf lettuce during the spring and fall, it is best to grow several plantings during each season. In the South, head lettuce is generally more difficult to grow than leaf lettuce. Lettuce does not tolerate hot weather. If this crop is exposed to high temperature or moisture stress, the lettuce will usually have a bitter flavor and will also bolt.

Lettuce seedlings are poor competitors with weeds; therefore, weed control is very important with this crop. Cultivation for weed control should be shallow to prevent root injury.

Tipburn is a physiological disorder that can occasionally occur on lettuce and is caused by calcium deficiency. High temperatures, uneven watering, windy conditions, using ammoniacal forms of nitrogen (use calcium nitrate, 15.5-0-0 instead to sidedress the crop), and rapid growth may all contribute to tipburn, but drought and not keeping the soil evenly moist are the most significant causes of this nutrient disorder. Proper soil pH and watering will help avoid this problem.

Excellent lettuce can be grown all winter in South Carolina. However, on extremely cold nights, it may be necessary to cover the crop with a portable miniature plastic covered hoop house or cover the row with a spun-bonded polypropylene. For example, a light to medium weight spun-bonded polypropylene will provide 4 degrees of frost protection down to 28º F.

Another option is to grow the lettuce in a cold frame.

Growing lettuce in a cold frame will provide protection on cold nights.

Growing lettuce in a cold frame will provide protection on cold nights.
Barbara H. Smith, ©2017 HGIC, Clemson Extension

Harvest & Storage

Leaf lettuce should be ready to harvest about 75 days after planting. It can be used as soon as plants are 5 to 6 inches tall. Bibb lettuce is mature when leaves begin to cup inward to form a loose head. Cos or Romaine is ready to use when the leaves have elongated and overlap to form a partially tight head about 6 to 8 inches tall.

Head lettuce can be harvested as early as 55 days, depending on the variety. It is mature when leaves overlap to form a head similar to those available in the stores.

Store in the refrigerator in the coolest area. Crisphead lettuce can be stored for two weeks under optimal conditions. Leaf and Bibb will store as long as four weeks if the leaves are dry when bagged.


Insect problems that may be encountered with this crop include aphids, cabbage looper, corn earworm, and leafhoppers. Diseases include gray mold, Rhizoctonia bottom rot, and Sclerotinia drop. Slugs and snails may feed on the foliage. If they become a problem, use an iron phosphate slug and snail bait. For examples of products containing iron phosphate, please see HGIC 2357, Snails & Slugs in the Home Garden.

Document last updated on 01/23 by Millie Davenport.

Originally published 12/99

If this document didn’t answer your questions, please contact HGIC at or 1-888-656-9988.

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